Research
Weill Cornell Medicine (WCM) is a global leader in pediatric health research.
- There are 34 open clinical trials in the Department of Pediatrics.
- WCM pediatrics faculty had 150 book chapters and articles published in peer-reviewed journals in 2017.
- 25 National Institutes of Health (NIH) awards were granted to 13 WCM pediatrics researchers between July 2017 and April 2018.
Children’s Health Investigators Fund Recipients
Each year, the Investigators Fund awards seed money to support three projects, providing early-career investigators with the resources needed to establish preliminary research results essential to qualify for substantial grants from the NIH. Below are the research projects the Investigators Fund has made possible.
Dr. Green’s research is focused on integrating behavioral and mental health care into pediatric practice. Through studying, implementing and disseminating interventions that can improve the skills of pediatricians, they can be trained to play a more effective role in the mental health care system. Dr. Green will study the impact of a three-year longitudinal curriculum for pediatric trainees on trainees’ mental health care competence and practices and patients’ access to mental health care and outcomes.
Dr. Scult’s primary research focus is understanding the neurobiology of resilience in adolescents and young adults. He is working to develop novel psychological interventions aimed at improving treatment of youth anxiety disorders. In his current project, Dr. Scult is using neuroimaging-based markers to identify personalized strategies that increase an adolescent’s or young adult’s engagement with digital mental health interventions that target anxiety.
Dr. Smith-Raska studies how a person’s life experiences such as stress, diet and exposure to medications or toxins cause abnormalities in germ cells (sperm and eggs), which then predispose their children and grandchildren to develop pediatric diseases such as autism and congenital cardiac disease. Dr. Smith-Raska is working to define a cellular signaling pathway that he hypothesizes is critical to explaining how environmental experiences and exposures are processed into stable, inheritable modifications in sperm and eggs.
Faith Gunning, PhD
Associate Professor of Psychology in Clinical Psychiatry
Vice Chair for Research and Psychology, Department of Psychiatry
Drs. Shannon Bennett, Avital Falk, Faith Gunning, Rebecca Jones and Conor Liston are bringing precision medicine to the treatment of anxiety and depression in youth. In partnership with The Wharton School of the University of Pennsylvania, the researchers use brain connectivity patterns to personalize app-based Cognitive Behavioral Therapy (CBT) for adolescents. The team uses brain imaging to better understand whose symptoms improve with app-based CBT and whose persist.
Dr. Perdita Permaul is the principal investigator on a research project evaluating the role that body mass index (BMI) plays in the relationship between inflammation and asthma morbidity in an established cohort of urban children with asthma. The data collected through this research will reveal potential biomarkers linking obesity and asthma, thereby providing better insight into the connection between these two chronic diseases.
Dr. Amy Tsou’s research is focused on understanding how intestinal bacteria and the nervous system interact with the immune system, and how these interactions influence intestinal inflammation in inflammatory bowel disease (IBD). She hopes to identify a new generation of therapies that can improve outcomes for the 1.6 million Americans – and 140,000 children – who suffer from this lifelong disease.
Melody Zeng, PhD
Assistant Professor of Immunology in Pediatrics
Member, Gale and Ira Drukier Institute for Children’s Health
The primary focus of research in Dr. Zeng’s laboratory is to study how gut immune cells and bacteria interact at the maternal-fetal/neonatal interface in the context of pediatric inflammatory diseases. The goal of the research is to develop strategies to use beneficial gut bacteria as candidates for maternal vaccinations to help protect babies from the type of inflammation that could lead to autoinflammatory diseases.
